16. A 50 year old woman developed a persistent cough. A plain-film chest radiograph showed a rounded 5 cm. mass in the anterior mediastinum (top left). After a fine needle aspiration biopsy was done (top right & bottom left), surgical excision was performed (bottom middle & right).
Diagnosis = Castleman disease, unicentric hyaline-vascular type.
https://en.wikipedia.org/wiki/Castleman's_disease
https://en.wikipedia.org/wiki/Benjamin_Castleman
17. A 3 year old Mexican immigrant child was brought to medical attention by his parents, because of a rapidly-enlarging mass in the right orbit. On physical examination, marked right-sided proptosis was apparent, with suffusion of the surrounding soft tissues. An orbital exenteration was performed, yielding the specimen shown here.
Diagnosis = Retinoblastoma
https://en.wikipedia.org/wiki/Retinoblastoma
Diagnosis = Retinoblastoma
https://en.wikipedia.org/wiki/Retinoblastoma
18. A 78 year old man had had annular patches and plaques over much of his body for 5 years. He now presents with nodular and partially necrotic lesions in the skin of the foot.
Diagnosis = Transformed Mycosis Fungoides, Acral Necrotizing Type
http://bloodjournal.hematologylibrary.org/content/95/7/2212.long
Diagnosis = Transformed Mycosis Fungoides, Acral Necrotizing Type
http://bloodjournal.hematologylibrary.org/content/95/7/2212.long
19. A 41 year old woman was given oral trimethoprim-sulfamethoxazole for a urinary tract infection. Five days later, she developed the cutaneous eruption shown here. The skin biopsy specimen is also illustrated.
Dx = Erythema multiforme
http://en.wikipedia.org/wiki/Erythema_multiforme
Dx = Erythema multiforme
http://en.wikipedia.org/wiki/Erythema_multiforme
20. 44 year old man with right testicular mass, found preoperatively to have a serum bHCG level of 500 IU/L. The clinical suspicion was that a choriocarcinomatous component would be present.
Dx = "Pure" Seminoma Containing Scattered Syncytiotrophoblastic Cells ( a Biochemical Simulant of Choriocarcinoma)
http://en.wikipedia.org/wiki/Seminoma
Dx = "Pure" Seminoma Containing Scattered Syncytiotrophoblastic Cells ( a Biochemical Simulant of Choriocarcinoma)
http://en.wikipedia.org/wiki/Seminoma